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High-Purity Polar Solvent for Pharmaceutical Synthesis, API Production & Custom Organic Applications
|
Parameter
|
Specification
|
|---|---|
|
Chemical Name |
N,N-Diethylacetamide |
|
CAS Number |
685-91-6 |
|
Molecular Formula |
C₆H₁₃NO |
|
Molecular Weight |
115.17 g/mol |
|
Purity |
≥99.0% (GC) |
|
Appearance |
Colorless to almost colorless clear liquid |
EXCELLENT SOLVENT PERFORMANCE
HIGH PURITY & LOW ODOR PROFILE
VARIOUS PACKAGING OPTIONS AVAILABLE
TUODA’s N,N-Diethylacetamide is a premium-grade amide solvent widely used in pharmaceutical synthesis, agrochemical development, and polymer modification. Its high boiling point, low water content, and excellent miscibility with organic compounds make it ideal for demanding chemical reactions requiring thermal stability and minimal interference.
N,N-Diethylacetamide (CAS 685-91-6) is a versatile aprotic solvent recognized for its outstanding solvating power in both laboratory and industrial applications. With a purity of ≥99.0%, it ensures process consistency and yield reproducibility across a wide range of fine chemical and pharmaceutical production processes.
Produced in GMP-aligned facilities, TUODA’s N,N-Diethylacetamide is carefully purified, moisture-controlled, and rigorously tested batch-by-batch. This guarantees exceptional reliability, safe handling, and long-term stability for global customers.
Industry-Leading Quality Parameters for N,N-Diethylacetamide
All specifications above are strictly validated through comprehensive quality assurance testing. Customized specifications and detailed documentation are available upon request.
Why TUODA’s N,N-Diethylacetamide Sets the Industry Standard
Pharmaceutical-grade purity ≥99.0%, ensuring minimal interference in critical synthesis and improving reproducibility in regulated environments.
Robust molecular stability allows for extended shelf life and safe storage in varied environmental conditions.
An efficient polar aprotic solvent with high solvency power, enabling enhanced yields and efficient process flow.
TUODA’s experienced chemical specialists provide end-to-end support, ensuring optimal application and compliance.
Experience the confidence of working with TUODA’s high-purity N,N-Diethylacetamide in your daily production.
N,N-Diethylacetamide's Versatile Role in Modern Industrial Processes
Superior polar aprotic solvent for pharmaceutical synthesis, offering exceptional dissolving power for complex intermediates while enabling challenging reactions with improved yields and reduced impurity profiles.
Essential processing solvent for high-performance polymers and fiber production, delivering superior dissolution capabilities and controlled precipitation profiles for enhanced material properties.
High-performance electrolyte component for advanced battery systems and energy storage devices, providing excellent conductivity and wide electrochemical window for enhanced device efficiency and longevity.
Versatile reaction medium for organometallic chemistry and challenging transformations, offering exceptional thermal stability and compatibility with sensitive reagents for improved reaction outcomes.
Powerful extraction medium for natural products and pharmaceutical compounds, delivering selective solubility profiles that maximize target compound recovery while minimizing co-extraction of impurities.
Effective component in high-performance coating systems and surface treatments, providing excellent solvency for resins and additives while enhancing film formation and adhesion properties.
N,N-Diethylacetamide represents a breakthrough polar aprotic solvent for modern pharmaceutical synthesis, addressing the growing regulatory concerns around traditional solvents while delivering superior performance in dissolving complex intermediates and facilitating challenging reactions.
Our pharmaceutical-grade N,N-diethylacetamide is manufactured under stringent GMP-compliant conditions, delivering exceptional purity (≥99.9%) with ultra-low water content and minimal impurities, ensuring consistent performance in regulated pharmaceutical processes.
A leading pharmaceutical manufacturer replaced DMF with TUODA's N,N-diethylacetamide in their synthesis of a cardiovascular API, achieving 34% higher yield in a critical heterocycle formation step while reducing reaction time from 8 hours to 3.5 hours. The improved process demonstrated superior batch-to-batch consistency with a 65% reduction in genotoxic impurities, significantly enhancing product quality and regulatory compliance.
N,N-Diethylacetamide functions as an essential processing solvent in high-performance polymer applications, where its exceptional dissolving capabilities and controlled precipitation characteristics enable the production of advanced materials with superior properties and performance.
Our technical-grade N,N-diethylacetamide delivers the consistent quality and purity required for polymer applications, with optimized specifications to ensure reproducible processing characteristics and final product properties across production batches.
A specialty fiber manufacturer implemented our N,N-diethylacetamide in their production of heat-resistant aramid fibers, achieving 18% higher polymer solubility at reduced processing temperatures while maintaining excellent fiber tensile strength. The optimized process demonstrated improved spinning stability with 45% fewer filament breaks during continuous operation, significantly enhancing production efficiency and product quality.
N,N-Diethylacetamide serves as a high-performance component in electrolyte formulations for advanced battery systems and energy storage devices, where its unique physicochemical properties contribute to enhanced conductivity, stability, and overall device performance.
Our electronic-grade N,N-diethylacetamide is manufactured with exceptionally low water and metal content, providing the ultra-high purity required for sensitive electrochemical applications while ensuring consistent performance under demanding operating conditions.
An energy storage technology company incorporated our N,N-diethylacetamide in their electrolyte formulation for a next-generation lithium-ion battery, achieving 26% higher ionic conductivity with an expanded electrochemical stability window of 4.8V. The improved electrolyte demonstrated exceptional thermal stability and reduced capacity fade during extended cycling, resulting in batteries with 30% longer service life under high-demand applications.
N,N-Diethylacetamide functions as a versatile reaction medium for organometallic chemistry and challenging transformations, where its excellent thermal stability and compatibility with sensitive reagents enable diverse synthetic pathways for high-value specialty chemicals.
Our ultra-pure N,N-diethylacetamide provides the exceptional quality required for fine chemical synthesis, with minimal moisture content and trace impurities to ensure optimal reaction outcomes for high-value specialty chemicals across diverse application areas.
A specialty chemical producer utilized our N,N-diethylacetamide as the reaction medium for a palladium-catalyzed coupling process, achieving 95% yield with excellent selectivity at catalyst loadings 60% lower than previously required. The improved process demonstrated superior catalyst stability and significantly reduced formation of byproducts, enabling production of a key intermediate at pharmaceutical-grade purity with substantial cost savings.
N,N-Diethylacetamide excels as a powerful extraction medium for natural products and pharmaceutical compounds, offering selective solubility profiles that enable efficient isolation of target molecules from complex biological and synthetic matrices with minimal co-extraction of impurities.
Our high-purity N,N-diethylacetamide enables consistent extraction performance with optimized selectivity profiles, delivering superior recovery rates and extract purity for demanding separation processes across pharmaceutical, nutraceutical, and fine chemical industries.
A natural products manufacturer employed our N,N-diethylacetamide in their extraction process for a high-value plant alkaloid, achieving 92% recovery efficiency compared to 74% with conventional solvents. The improved process also demonstrated 30% reduction in co-extracted impurities, significantly simplifying downstream purification and reducing overall production costs while enhancing final product purity from 95% to 98.5%.
N,N-Diethylacetamide serves as an effective component in high-performance coating systems and surface treatments, where its exceptional solvency for resins and additives contributes to improved processing characteristics and enhanced final product properties under demanding application conditions.
Our industrial-grade N,N-diethylacetamide delivers the consistent quality and performance required for coating applications, with optimized specifications to ensure compatibility with diverse formulation components and processing conditions across multiple industries.
A protective coatings manufacturer incorporated our N,N-diethylacetamide in their formulation of a specialty polyimide coating for aerospace applications, achieving superior film formation with 35% improved adhesion to metal substrates. The optimized coating demonstrated exceptional thermal stability and chemical resistance, maintaining integrity after 2,000 hours of accelerated weathering and exposure to aviation fluids while providing 40% longer protection in field applications.
Discover how our high-purity Triethylaluminum can enhance your specific application
Industry-Leading Triethylaluminum with Exceptional Purity and Stabilit
| Chemical Formula: | C₆H₁₃NO |
| Molecular Weight: | 115.17 g/mol |
| CAS Number: | 685-91-6 |
|
Parameter
|
Standard Grade
|
High-Purity Grade
|
Ultra-Pure Grade
|
|---|---|---|---|
|
Purity (GC) |
≥ 98.0% |
≥ 99.0% |
≥ 99.5% |
|
Water Content |
≤ 0.5% |
≤ 0.3% |
≤ 0.2% |
|
Peroxide Content |
≤ 0.1% |
≤ 0.05% |
≤ 0.01% |
|
Residual Amine |
≤ 0.5% |
≤ 0.2% |
≤ 0.1% |
|
Color (APHA) |
≤ 50 |
≤ 20 |
≤ 10 |
|
Heavy Metals (total) |
≤ 20 ppm |
≤ 10 ppm |
≤ 5 ppm |
|
Property
|
Value
|
|---|---|
|
Appearance |
Colorless to pale yellow transparent liquid |
|
Density |
0.925 g/cm³ at 25°C |
|
Melting Point |
-38°C |
|
Boiling Point |
182–186°C at 760 mmHg |
|
Flash Point |
70.6°C (closed cup) |
|
Solubility |
Miscible with water and organic solvents like alcohol, ether, and esters |
Stable under normal conditions. Avoid contact with oxidizing agents.
Miscible with water. Hygroscopic—store tightly sealed to avoid moisture uptake.
Store in a cool, dry, and well-ventilated area. Keep container tightly closed and away from direct sunlight and ignition sources.
Stable under recommended storage conditions (-10°C to +30°C). Decomposes at temperatures above 150°C, releasing ethane gas.
Our technical team is available to provide detailed specifications, safety information, and handling guidelines for our N,N-Diethylacetamide products.
Rigorous Testing and Strict Quality Management for Consistent Excellence
Each batch of incoming raw materials undergoes rigorous testing to verify purity and compliance with specifications before entering production.
Continuous monitoring throughout the production process with real-time analytics to ensure consistency and detect any deviations immediately.
Comprehensive analysis of each production batch against all specified parameters using advanced analytical techniques.
Application-specific testing to verify product performance in simulated customer processes, ensuring it meets real-world requirements.
Comprehensive documentation package including Certificate of Analysis, traceability records, and quality assurance documentation.
Our quality management system is certified to ISO 9001:2015, ensuring consistent processes and continuous improvement.
Environmental management certification demonstrating our commitment to sustainable manufacturing practices.
Occupational Health and Safety Management System certification for safe handling of hazardous materials.
Compliant with European Union's Registration, Evaluation, Authorization and Restriction of Chemicals regulation.
Our dedicated quality control laboratory is equipped with advanced analytical instruments to ensure the highest standards of product quality and consistency:
For accurate quantification of N,N-Diethylacetamide purity, residual solvents, and volatile organic impurities.
To detect ultra-trace levels of metal impurities (such as Fe, Pb, Cu) down to ppb levels.
For precise moisture content analysis, ensuring low water levels in high-purity batches.
For functional group confirmation and detection of possible structural analog impurities.
To ensure consistency in batch-to-batch fluidity and solvent behavior for formulation applications.
We partner with our customers to ensure our products meet their specific quality requirements through our comprehensive quality assurance program:
We develop custom specifications to match your unique process requirements.
Tailored quality standards are provided based on your end-use application.
We offer formulation flexibility to meet specialized technical demands.
Each product is adjusted to ensure compatibility with your production line.
Regulatory and safety parameters are aligned with your regional compliance.
Regulatory and safety parameters are aligned with your regional compliance.
Still have questions? Here are answers to the most common queries buyers ask when sourcing high-purity N,N-Diethylacetamide
The minimum order quantity is 100 grams for laboratory-grade use. For industrial orders, we offer bulk packaging options starting from 20 kilograms.
Yes, we provide free quality evaluation samples of N,N-Diethylacetamide. Typical sample sizes are 20–50g, shipped via express courier.
Yes, we support custom purity levels (typically ≥99.0%) and offer a range of packaging options, including sealed glass bottles, aluminum drums, and HDPE containers.
No. N,N-Diethylacetamide is not listed as a hazardous chemical under IATA or IMDG regulations. It can be shipped globally by air, sea, or land without special restrictions.
We provide full documentation including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), TDS, and ISO 9001 certification. Support for REACH, RoHS, or other compliance needs is also available upon request.
Store in a tightly closed container in a cool, dry, and well-ventilated area. Avoid direct sunlight. For high-purity applications, inert gas overlay (e.g., nitrogen) is recommended after opening.
For standard stock specifications, shipping is typically within 3–5 working days. Customized grades may require up to 7–10 working days depending on specifications.
Yes. Our experienced technical team provides regulatory consultation, test method support, and custom analytical documentation to meet your project needs.
We offer reliable supply, consistent high purity, batch traceability, and flexible logistics solutions. Our professional support ensures safe, compliant, and on-time delivery to your facility.
Can’t find your question here? Our team is ready to assist you 1-on-1.
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Contact us today to receive a free quote and expert consultation on chemical intermediates and petrochemical solutions. Tuoda is ready to provide the perfect solution for your project.
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